The Public Health Fundamentals explore the essential pillars of HPV prevention, from the global epidemiology of infection to the practical implementation of life-saving policies.

The first session provides an orientation into the epidemiology of HPV and its related diseases, examining the burden and prevention opportunities across specific anatomic sites. Experts will review infection prevalence, transmission, and progression to disease, alongside a high-level analysis of attributable fractions for various cancers. This segment places a heavy emphasis on health inequalities and regional variations, covering the diversity of cervical infection, male transmission risks, and the unique challenges of screening for vaginal, vulvar, and oral-track diseases.

The second segment shifts focus to primary and secondary prevention strategies, outlining the “vaccinate–screen–treat” paradigm. Speakers will trace the evolution of HPV vaccination strategies—including updates on valency, dosing, and real-world effectiveness—and review current cervical screening recommendations, such as the adoption of self-sampling and primary HPV testing. This session also explores the early stages of anal cancer screening implementation and the specific considerations required for high-risk populations.

The track concludes with a session dedicated to the implementation strategies that support large-scale prevention goals. Participants will learn how public health programs are selected, evaluated, and forecasted using mathematical modeling and health economics. Key discussions will center on achieving the WHO targets for vaccine coverage, screening, and treatment, with a focus on overcoming vaccine hesitancy, debunking misinformation, and leveraging modern communication tools to ensure effective policy delivery across global regions.